Dr Mandy CHU Man Yee

Specialist in Gynaecological Oncology

Honorary Clinical Associate Professor, Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, HKU

HEAL Medical

HEAL Fertility

Qualification
  • MB BS (HK)
  • FHKAM (Obstetrics and Gynaecology)
  • FHKCOG
  • Cert RCOG (Gynae Onc)
  • FRCOG
Consultation Hours
MON - FRI8:30am-5:30pm

Scope of Services

  • Surgery for benign and malignant gynaecological conditions, including hysteroscopy, laparoscopy, robotic-assisted operation and laparotomy
  • Hereditary Cancers
  • Uterine cancer
  • Ovarian cancer / borderline ovarian tumour
  • Cervical cancer
  • Vaginal and vulval cancer
  • Cervical screening – Pap smear and HPV tests
  • Colposcopy-related procedure for pre-malignant condition (intra-epithelial neoplasia) of the lower female genital tract
  • Ovarian cyst
  • Endometriosis
  • Fibroid and Adenomyosis
  • Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
  • Dysmenorrhea
  • Abnormal menstrual cycle & uterine bleeding
  • Contraception
  • Menopause
  • HPV vaccine

Admission Rights

  • Gleneagles Hospital
  • Baptist Hospital

Publications

  • Chan K.K.L., Chai Y.K.V., Cheung V.Y.T., Choi K.M.C., Chu M.Y.M., Siu K.Y., Tse K.Y. and Ngan H.Y.S., Use of ultrasonographic rules and tumour marker HE4 level to predict malignancy of a pelvic mass: abridged secondary publication, Hong Kong Med J. 2022
     
  • Ngu S.F., Tse K.Y., Chu M.Y.M., Ngan H.Y.S. and Chan K.K.L., Olaparib dose re-escalation in ovarian cancer patients who experienced severe and/or uncommon adverse events: A case series., Asia Pac J Clin Oncol.. 2021, 17, 3-11. http://dx.doi.org/10.1111/ajco.13584
     
  • Chan K.K.L., Liu S., Wei N., Ngu S.F., Chu M.Y.M., Tse K.Y., Lau S.K., Cheung A.N.Y. and Ngan H.Y.S., Primary HPV testing with cytology versus cytology alone in cervical screening—A prospective randomized controlled trial with two rounds of screening in a Chinese population , International Journal of Cancer. 2020. http://dx.doi.org/10.1002/ijc.32861
     
  • Liu S., Chan K.K.L., Chu K.H., Wei N., Lau S.K., Ngu S.F., Chu M.Y.M., Tse K.Y., Ip P.C.P., Ng E.K.O., Cheung A.N.Y. and Ngan H.Y.S., Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer, 2018. http://dx.doi.org/10.1002/1878-0261.12383(Publication No. : 294143)
     
  • Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69. http://dx.doi.org/10.12892/ejgo3763.2018 (Publication No. : 284270)
     
  • Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018. http://dx.doi.org/10.1093/ajcp/aqy039 (Publication No. : 285802)
     
  • Ngu SF, Chu MM, Ip PP, Ngan HY. Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? J Obstet Gynaecol Can. 2017 Mar 30. S1701-2163(16)39741-9.
     
  • Ngu SF, Wei N, Kwan TT, Chu MM, Tse KY, Chan KK, Ngan HY. Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial. J Psychosom Obstet Gynaecol. 2017 Apr 10:1-10.
     
  • SF Ngu, N Wei, TTC Kwan, MMY Chu, KY Tse, KKL Chan, HYS Ngan. Impact of different educational interventions on psychosocial wellbeing of Hong Kong Chinese women with a positive high-risk human papillomavirus and normal cervical cytology. Journal of Psychosomatic Obstetrics & Gynecology 2017: 10: 1 – 10.
     
  • Chu MM, Tse KY, Chan KK, Cheung AN, Ngan HY. Placental site trophoblastic tumour – a distinct entity of gestational trophoblastic disease: experience from a tertiary referral center in Hong Kong. J Reprod Med. 2016 Aug;61(4):351-6
     
  • Chu MM, Ma Y, Tse KY, Chan KK, Ngan HY. Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia. International Journal of Gynecological Cancer 2015 Mar;25(3):498-503.
     
  • Chu MYM, Liu S, Tam KF, Ip PCP, Cheung ANY and Ngan HYS. The Significance of Mismatch Repair Deficiency in Young Patients With Endometrial Cancer. Int J Gynecol Pathology 2015, 34: 403-410.
     
  • Leung TW, Liu S, Leung CY, Chu MM, Cheung ANY and Ngan HYS. HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis. J Med Virol 2015, 2015 Jun;87(6):1022-33.
     
  • Lee EY, Khong PL, Tse KY, Chan KK, Chu MM, Ngan HY. Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. Nucl Med Commun. 2013; 34(12):1185-9.
     
  • Chu MM, Lee WC, Leung JL, Wong V. Modified symbolic play test for Oriental children. Pediatr Int. 2006; 48(6):519-24.
     
  • Au YL, Ma KM, Sy WM, Lee WC, Leung LS, Au Yeung YC, Chu MY, Chung CK, Ho PK, Lau WL, Law PK, Siu PY, Tse KS, Wong V. Brain Dev. Use of developmental language scales in Chinese children. 2004; 26(2):127-9.

Media Interviews

 

 

 

 

 

 

Related Services

Abnormal Menstrual Cycle & Uterine Bleeding

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Menstrual cycle and abnormal bleeding refer to variations in the length, flow, or duration of the menstrual cycle outside the normal range. Irregular menstrual cycles may include intervals between periods that are too long or too short, excessively heavy or light periods, and intermittent bleeding between periods. Abnormal uterine bleeding may involve bleeding outside of the menstrual period.

Adenomyosis

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Adenomyosis is a condition that affects the uterus in women. It occurs when the tissue from the inner lining of the uterus (endometrium) breaks through the uterine wall and develops into new endometrial tissue within the uterine muscle layer. This growth can cause the uterine tissue to enlarge and thicken, leading to various symptoms.

Cancer

Traditional Chinese Medicine (TCM)Clinical OncologyGeneral SurgeryGynaecological Oncology
Cancer is the generic name given to a cluster of related diseases. In a normal healthy body, human cells grow and divide as the body needs them. When cells become old or damaged, they die and new cells take their place. However, cancer relates to body cells dividing uncontrollably and spreading to neighbouring tissues.

Cervical Cancer

Clinical OncologyObstetrics and GynaecologyGynaecological Oncology
Cervical cancer, also known as cancer that occurs in the cervix, is statistically caused by HPV (Human Papillomavirus) infection in over 90% of cases, leading to abnormal cell growth and eventual development of cancer. Cervical cancer is one of the common cancers among women, and women of all age groups are at risk of developing cervical cancer. In Hong Kong, cervical cancer ranks the 7th most common cancer among women and the 9th leading cause of fatal cancer among women. In 2020, there were a total of 556 new cases recorded, with 159 fatalities.

Cervicitis

Obstetrics and GynaecologyReproductive Medicine
Cervicitis refers to the infected and inflamed condition of the cervical tissue. Cervicitis typically occurs when viruses or bacteria, introduced through sexual activity, miscarriage, childbirth, or uterine procedures, enter the cervix and cause inflammation.

Contraception

Reproductive Medicine General Practice
Contraception is a measure or method used to prevent pregnancy. These methods can be temporary or permanent, aimed at helping individuals choose whether and when to conceive while engaging in sexual activity.

Corpus Uteri Cancer

Clinical OncologyObstetrics and GynaecologyGynaecological Oncology
Corpus Uteri Cancer is a common gynaecological malignant tumour. Common symptoms include vaginal bleeding, lower abdominal pain, etc. Early screening and treatment are needed.

Dysmenorrhea

Obstetrics and GynaecologyGynaecological Oncology
Dysmenorrhea, also known as menstrual cramps or period pain, refers to the abdominal pain experienced by women during menstruation. This pain may be accompanied by lower back pain, headaches, nausea, diarrhoea, and other symptoms, and its severity and duration vary from person to person. Dysmenorrhea is a prevalent symptom that affects the quality of life of many menstruating women.

Endometriosis / Chocolate Cysts

Traditional Chinese Medicine (TCM)Obstetrics and GynaecologyGynaecological Oncology
Endometriosis is a condition where the lining of the uterus grows outside of the uterus and can cause pain, irregular periods and fertility problems in women. The most common places for the growths to appear are the ovaries, pelvis and abdomen, and if it affects the ovaries, it can cause cysts known as "chocolate cysts". Although there is no cure for endometriosis, symptoms can be managed with medication or surgery.

HIPEC

General SurgeryGynaecological Oncology
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a procedure within the abdominal cavity that combines localized hyperthermic treatment with chemotherapy.

Hysteroscopy

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Hysteroscopy is a medical procedure used to examine and treat uterine issues. One end of the hysteroscope is equipped with illumination and a camera, allowing doctors to directly observe the condition of the uterine lining by entering the uterus through the vagina without the need for open surgery.

Laparoscopy

General SurgeryReproductive Medicine Gynaecological Oncology
Laparoscopy is a minimally invasive surgical technique that involves inserting a laparoscope and other surgical instruments through one or several small incisions in the abdomen to examine and perform surgery on internal organs. A laparoscope is a long, tube-like instrument with a light source and camera at one end, which transmits images from inside the body to an external monitor, allowing doctors to view the internal situation.

Menopause Health Care & Treatments

General PracticeEndocrinology, Diabetes and Metabolism
Menopause is a natural transitional period that women experience, typically between the ages of 45 and 55, during which ovarian function gradually declines, leading to a decrease in oestrogen levels and the cessation of menstruation. During this stage, appropriate healthcare is crucial.

Ovarian Cancer

Clinical OncologyGeneral SurgeryGynaecological Oncology
The ovaries are a part of the female reproductive system, consisting of two small organs in the pelvic cavity on either side of the uterus. Their function is to produce eggs and female hormones. Ovarian cancer is one of the most common gynaecological cancers and has the highest mortality rate among female cancers.

Ovarian Cysts

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Ovarian Cysts refer to a sac-like structure filled with fluid or solid material formed within the ovaries of females. Ovarian cysts typically develop during ovulation and are generally benign, but certain diseases can also cause them.

Vaginitis

Obstetrics and GynaecologyGynaecological Oncology
Vaginitis is a common gynaecological condition, referring to the inflammation of the tissues inside the vagina. It can be caused by bacteria, fungi, viruses, or other microorganisms, leading to discomfort and inflammatory responses in the vaginal area."

Peritoneal Cancer

Clinical OncologyGeneral SurgeryGynaecological Oncology
Peritoneal cancer is a rare but severe form of cancer that involves malignant changes in the peritoneal tissues. The peritoneum is the thin membrane that surrounds the abdominal organs, and peritoneal cancer typically occurs due to metastasis from cancers originating in other organs within the abdominal cavity. In Hong Kong, peritoneal cancer is most commonly caused by the metastasis of ovarian cancer, making the incidence higher in female patients.

Polycystic Ovary Syndrome

Traditional Chinese Medicine (TCM)Obstetrics and GynaecologyReproductive Medicine Endocrinology, Diabetes and Metabolism
Polycystic Ovary Syndrome (PCOS) is an endocrine disease affect the female reproductive system. Excessive male hormones are produced by the ovaries. As a result, patients may suffer from irregular period, difficulties in ovulation and reproductively challenged.

Uterine Fibroids

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Uterine Fibroids, also known as Uterine Leiomyomas, are non-cancerous tumours of the female reproductive organ. They typically develop in the muscular layer of the uterus and are considered benign tumours. Uterine fibroids are a common gynaecological issue, especially among women of reproductive age.

Uterine Polyps

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Uterine Polyps refer to benign tumours formed by the overgrowth of mucosal cells in the uterine cavity. It can be further classified as an endometrial and cervical polyp based on its growth location. Uterine polyps may cause mild bleeding or discomfort and are typically discovered during routine gynaecological examinations in women.

Uterine Prolapse

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Uterine Prolapse refers to the partial or complete descent of the uterus from its normal position. The pelvic floor muscles and ligaments usually support the uterus. When these muscles or ligaments become damaged or weakened, the uterus may gradually descend towards the opening of the vagina, leading to what is known as uterine prolapse.

Pelvic Inflammatory Disease

Obstetrics and GynaecologyReproductive Medicine Gynaecological Oncology
Pelvic Inflammatory Disease (PID) is one of the common gynaecological conditions, referring to the condition where there is an infection and inflammation in the pelvic organs of the female reproductive system, including the uterus, fallopian tubes, and ovaries. As PID is often caused by bacterial infections, especially those transmitted through sexual contact, it is more prevalent among young women aged 15 to 44.

Vaginal Itching

Obstetrics and GynaecologyGeneral PracticeGynaecological Oncology
Vaginal Itching refers to the itching sensation in the external genital area of women, which may be accompanied by other symptoms such as redness, burning sensation, increased discharge, or an unusual odour. Various factors, including infections, skin inflammation, allergic reactions, hormonal changes, etc, can cause Vaginal Itching.

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