Dr Terence TAM Chi Chun
Specialist in Respiratory Medicine
Honorary Clinical Assistant Professor, Department of Medicine, The University of Hong Kong
Qualifications
- MBBS (HK)
- MRCP (UK)
- FRCP (Edin)
- FRCP (Glasg)
- FRCP (Lond)
- FHKCP
- FHKAM (Medicine)
Scope of services
- Asthma/Airway Allergy
- Chronic Obstructive Pulmonary Disease (COPD)
- Infectious Pneumonia
- Lung Nodule/Lung Shadow
- Tuberculosis
- Mediastinal Diseases
- Lung Cancer
- Sleep Apnoea
- Interstitial Lung Diseases
- Pleural Diseases
- Therapeutic Bronchoscopy
- Advanced Diagnostic Bronchoscopy
- Respiratory Failure
Publications
- Kwok, W. C., Chau, C. H., Tam, T. C. C., Lam, F. M., & Ho, J. C. M. (2023). Variability of Blood Eosinophil Count at Stable-State in Predicting Exacerbation Risk of Chronic Obstructive Pulmonary Disease. International journal of chronic obstructive pulmonary disease, 18, 1145–1153.
- Kwok, W. C., Tam, T. C. C., Lam, D. C. L., Ip, M. S. M., & Ho, J. C. M. (2023). Blood eosinophil percentage as a predictor of response to inhaled corticosteroid in bronchiectasis. The clinical respiratory journal, 17(6), 548–555.
- Kwok, W. C., Tam, T. C. C., Sing, C. W., Chan, E. W. Y., & Cheung, C. L. (2023). Validation of diagnostic coding for bronchiectasis in an electronic health record system in Hong Kong. Pharmacoepidemiology and drug safety, 1-6.
- Kwok, W. C., Ma, T. F., Ho, J. C. M., Lam, D. C. L., Sit, K. Y., Ip, M. S. M., Au, T. W. K., & Tam, T. C. C. (2023). Prediction model on disease recurrence for low risk resected stage I lung adenocarcinoma. Respirology (Carlton, Vic.), 28(7), 669–676
- Kwok, W. C., Tam, T. C. C., Sing, C. W., Chan, E. W. Y., & Cheung, C. L. (2023). Validation of Diagnostic Coding for Asthma in an Electronic Health Record System in Hong Kong. Journal of asthma and allergy, 16, 315–321.
- Kwok, W. C., Tsoi, M. F., Leung, S. H. I., Tsui, C. K., Tam, T. C. C., Ho, J. C. M., Lam, D. C. L., Ip, M. S. M., & Ho, P. L. (2023). Real-World Study on Effectiveness of Molnupiravir and Nirmatrelvir-Ritonavir in Unvaccinated Patients with Chronic Respiratory Diseases with Confirmed SARS-CoV-2 Infection Managed in Out-Patient Setting. Viruses, 15(3), 610.
- Kwok, W. C., Tam, T. C. C., Lam, D. C. L., Leung, J. K. C., Chan, K. P. F., Chan, S. K. S., Chiang, K. Y., Ip, M. S. M., & Ho, J. C. M. (2023). Worsening of asthma control after recovery from mild to moderate COVID-19 in patients from Hong Kong. Respiratory research, 24(1), 53.
- Kwok, W. C., Leung, S. H. I., Tam, T. C. C., Ho, J. C. M., Lam, D. C., Ip, M. S. M., & Ho, P. L. (2023). Efficacy of mRNA and Inactivated Whole Virus Vaccines Against COVID-19 in Patients with Chronic Respiratory Diseases. International journal of chronic obstructive pulmonary disease, 18, 47–56.
- Zouari, F., Oon, W. Y., Modak, D., Lee, W. H., Kwok, W. C., Cao, P., Lee, W. N., Tam, T. C. C., Wong, E. C., & Chan, R. W. (2022). Affordable, portable and self-administrable electrical impedance tomography enables global and regional lung function assessment. Scientific reports, 12(1), 20613.
- Zouari, F., Oon, W. Y., Modak, D., Kwok, W. C., Cao, P., Lee, W. N., Tam, T. C. C., Wong, E. C., & Chan, R. W. (2022). Standalone electrical impedance tomography predicts spirometry indicators and enables regional lung assessment. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022, 3277–3280.
- Duan, J., Tan, F., Bi, N., Chen, C., Chen, K. N., Cheng, Y., Chu, Q., Ge, D., Hu, J., Huang, Y., Jiang, T., Long, H., Lu, Y., Shi, M., Wang, J., Wang, Q., Yang, F., Yang, N., Yao, Y., Ying, J., … Gao, S. (2022). Expert consensus on perioperative treatment for non-small cell lung cancer. Translational lung cancer research, 11(7), 1247–1267.
- Kwok, W. C., Lam, D. C. L., Ip, M. S. M., Tam, T. C. C., & Ho, J. C. M. (2022). Association of genetic polymorphisms of CYP3A4 and CYP2D6 with gefitinib-induced toxicities. Anti-cancer drugs, 33(10), 1139–1144.
- Kwok, W. C., Ho, J. C. M., Tam, T. C. C., Ip, M. S. M., & Lam, D. C. L. (2022). Serum protein level as a predictor of therapeutic response and adverse effects associated with afatinib use. Journal of thoracic disease, 14(6), 1880–1889.
- Kwok, W. C., Ho, J. C. M., Tam, T. C. C., Ip, M. S. M., & Lam, D. C. L. (2022). Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first-line setting. Thoracic cancer, 13(14), 2057–2063.
- Kwok, W. C., Cheong, T. F., Chiang, K. Y., Ho, J. C. M., Lam, D. C. L., Ip, M. S. M., & Tam, T. C. C. (2023). Clinical efficacy and safety of pemetrexed with or without either Bevacizumab or Pembrolizumab in patients with metastatic nonsquamous non-small cell carcinoma. Asia-Pacific journal of clinical oncology, 19(1), 87–95.
- Wang, A., Tam, T. C. C., Poon, H. M., Yu, K.-C., and Lee, W.-N., “NaviAirway: a Bronchiole-sensitive Deep Learning-based Airway Segmentation Pipeline”, <i>arXiv e-prints</i>, 2022.
- Kwok, W. C., Tam, A. R., Ho, J. C. M., Lam, D. C. L., Tam, T. C. C., Chan, K. P. F., Wang, J. K. L., Ip, M. S. M., & Hung, I. F. N. (2022). Asthma, from mild to severe, is an independent prognostic factor for mild to severe Coronavirus disease 2019 (COVID-19). The clinical respiratory journal, 16(4), 293–300.
- Chi-Chun Tam, T., & Chung-Man Ho, J. (2021). Navigational bronchoscopy: we should choose to do it not because it´s easy, but because it´s hard. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 25(1), 1–2.
- Kwok, W. C., Chiang, K. Y., Ho, J. C. M., Lam, D. C. L., Ip, M. S. M., & Tam, T. C. C. (2021). Risk factors of nephrotoxicity of maintenance pemetrexed in patients with metastatic non-squamous non-small cell carcinoma of lung. Lung cancer (Amsterdam, Netherlands), 162, 169–174.
- Kwok, W. C., Wong, C. K., Ma, T. F., Ho, K. W., Fan, L. W., Chan, K. F., Chan, S. S., Tam, T. C., & Ho, P. L. (2021). Modelling the impact of travel restrictions on COVID-19 cases in Hong Kong in early 2020. BMC public health, 21(1), 1878.
- Kwok, W. C., Ho, J. C. M., Tam, T. C. C., Ip, M. S. M., & Lam, D. C. L. (2021). Risk factors for Pseudomonas aeruginosa colonization in non-cystic fibrosis bronchiectasis and clinical implications. Respiratory research, 22(1), 132.
- Chan, K. F., Kwok, W. C., Ma, T. F., Hui, C. H., Tam, T. C., Wang, J. K., Ho, J. C., Lam, D. C., Sau-Man Ip, M., & Ho, P. L. (2021). Territory-Wide Study on Hospital Admissions for Asthma Exacerbations in the COVID-19 Pandemic. Annals of the American Thoracic Society, 18(10), 1624–1633.
- Kwok, W. C., Cheong, T. F., Chiang, K. Y., Ho, J. C. M., Lam, D. C. L., Ip, M. S. M., & Tam, T. C. C. (2021). Haematological toxicity of pemetrexed in patients with metastatic non-squamous non-small cell carcinoma of lung with third-space fluid. Lung cancer (Amsterdam, Netherlands), 152, 15–20.
- Zeng, Z., Yan, B., Chen, Y., Zhang, L., Zhu, J., Yang, F., Wei, F., Tam, T. C. C., Kauffmann-Guerrero, D., Soo, R. A., Ren, X., & You, J. (2020). Survival benefit and toxicity profile of adjuvant icotinib for patients with EGFR mutation-positive non-small cell lung carcinoma: a retrospective study. Translational lung cancer research, 9(6), 2401–2410.
- Kwok, C. W., Ho, J. C. M., Lam, D. C. L. , Sze M. L. M., Ip, M. S. M.and Tam, T. C. C. *, Clinical Impact of Gastric Acid Suppressants Use on the Efficacy of Gefitinib in Patients with Advanced Adenocarcinoma of the Lung Harboring Common EGFR Mutations, Clinical Cancer Drugs 2020; 7: 57
- Kwok, W. C., Lam, D. C. L., Chiang, K. Y., Ho, J. C. M., Ip, M. S. M., & Tam, T. C. C. (2020). Real world experience on maintenance chemotherapy with gemcitabine in second line setting for advanced non-small cell lung carcinoma. Journal of chemotherapy (Florence, Italy), 32(8), 429–436.
- Tam T. (2020). Adjuvant EGFR-TKIs-based therapy: are we ready?. Translational lung cancer research, 9(4), 948–950.
- Chan, K. P. F., Ma, T. F., Kwok, W. C., Leung, J. K. C., Chiang, K. Y., Ho, J. C. M., Lam, D. C. L., Tam, T. C. C., Ip, M. S. M., & Ho, P. L. (2020). Significant reduction in hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in Hong Kong during coronavirus disease 2019 pandemic. Respiratory medicine, 171, 106085.
- Chiang, K. Y., Ho, J. C., Chong, P., Tam, T. C., Lam, D. C., Ip, M. S., Lee, Y. G., & Lui, M. M. (2020). Role of early definitive management for newly diagnosed malignant pleural effusion related to lung cancer. Respirology (Carlton, Vic.), 25(11), 1167–1173.
- Kwok, W. C., Ho, J. C. M., Lam, D. C. L., Lui, M. M. S., Ip, M. S. M., & Tam, T. C. C. (2021). When compared to plasma-based detection, osimertinib-treated non-small cell lung cancer (NSCLC) with tissue rebiopsy-confirmed acquired T790M mutation is associated with better survival. Asia-Pacific journal of clinical oncology, 17(2), e35–e39.
- Kwok, W. C., Ho, J. C. M., Tam, T. C. C., Lui, M. M. S., Ip, M. S. M., & Lam, D. C. L. (2019). Efficacy of gefitinib at reduced dose in EGFR mutant non-small cell lung carcinoma. Anti-cancer drugs, 30(10), 1048–1051.
- Kwok, W. C., Cheng, K. C., Lam, D. C. L., & Tam, T. C. C. (2019). First successful case of chemical pleurodesis with oxytetracycline through Rocket® Pleural Vent™: ambulatory pneumothorax device for pneumothorax. Respirology case reports, 7(7), e00471.
- Kwok, W. C., Liang, B. M., Lui, M. M. S., Tam, T. C. C., Sim, J. P. Y., Tse, E. W. C., Leung, A. Y. H., Kwong, Y. L., Lie, A. K. W., Ip, M. S. M., & Lam, D. C. L. (2019). Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome. Respirology (Carlton, Vic.), 24(5), 459–466.
- Kwok, W. C., Tam, T. C. C., & Lam, D. C. L. (2018). First reported case of afatinib-associated toxic megacolon. Respirology case reports, 6(7), e00360.
- Kwok, W. C., Tam, T. C. C., Chi Leung Lam, D., Ip, M. S. M., & Lui, M. M. S. (2018). Pulmonary embolism developing after therapeutic drainage of malignant pleural effusions. Respiratory medicine case reports, 25, 122–123.
- Terence Tam. Use of the New Veran Always-On Tip Tracked Sensor with Olympus GuideSheath System to Arrive at a Small Peripheral Ground-Glass Nodule. CHEST Volume 152, Issue 4, Supplement, Pages A641–A642
- Kwok, W. C., Tam, T. C., Lui, M. M., Lam, D. C., & Ho, J. C. (2017). Control of brain metastases with alectinib in anaplastic lymphoma kinase-rearranged lung cancer. Respirology case reports, 5(3), e00224.
- Lam, J. C. M., Lai, A. Y. K., Tam, T. C. C., Yuen, M. M. A., Lam, K. S. L., & Ip, M. S. M. (2017). CPAP therapy for patients with sleep apnea and type 2 diabetes mellitus improves control of blood pressure. Sleep & breathing = Schlaf & Atmung, 21(2), 377–386.
- Wong, W. M., Tam, T. C., Wong, M. K., Lui, M. M., Ip, M. S., & Lam, D. C. (2016). Managing malignant pleural effusion with an indwelling pleural catheter: factors associated with spontaneous pleurodesis. Hong Kong medical journal = Xianggang yi xue za zhi, 22(4), 334–340.
- Lam, D. C., Tam, T. C., Lau, K. M., Wong, W. M., Hui, C. K., Lam, J. C., Wang, J. K., Lui, M. M., Ho, J. C., & Ip, M. S. (2015). Plasma EGFR Mutation Detection Associated With Survival Outcomes in Advanced-Stage Lung Cancer. Clinical lung cancer, 16(6), 507–513.
- Ho, J. C., Tam, T. C., & Lam, S. K. (2013). Salvage therapy beyond targeted therapy in lung adenocarcinoma. Seminars in respiratory and critical care medicine, 34(6), 837–844.
- Ho, Tam, Lam, 2013. Personalized Treatment of Lung Adenocarcinoma, Clinical Pulmonary Medicine, 20(6), 309-314.
- Tam, T. C., Ho, J. C., Wong, M. K., Wong, W. M., Wang, J. K., Lam, J. C., Lui, M. M., Lam, W. K., Ip, M. S., & Lam, D. C. (2013). Treatment outcomes in elderly with advanced-stage non-small cell lung cancer. Lung, 191(6), 645–654.
- Wong, M. K., Ho, J. C., Loong, F., Lam, D. C., Wong, W. M., Tam, T. C., Han, L., & Ip, M. S. (2013). Endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer: the first experience in Hong Kong. Hong Kong medical journal = Xianggang yi xue za zhi, 19(1), 20–26.
- Wong, M. K., Tam, T. C., Lam, D. C., Ip, M. S., & Ho, J. C. (2012). EBUS-TBNA in patients presented with superior vena cava syndrome. Lung cancer (Amsterdam, Netherlands), 77(2), 277–280.
- Tam, T. C., Chan, K. Y., Ho, S. L., Luk, J. K., & Chu, L. W. (2005). Herpetic shoulder paresis in a Chinese elderly patient. Hong Kong medical journal = Xianggang yi xue za zhi, 11(5), 399–402.
Media Interviews
Services by the Doctor
Advanced Diagnostic Bronchoscopy
Respiratory Medicine
Advanced diagnostic bronchoscopies are cutting-edge procedures that enable the diagnosis and staging of lung diseases. The services include Endobronchial Ultrasound (EBUS), Virtual Bronchoscopy Navigation (VBN), Electromagnetic Navigation Bronchoscopy (ENB), and Dynamic Scan Guided Bronchoscopy Examination, among others.
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Asthma
Respiratory Medicine
Asthma is a chronic respiratory illness, which needs long term treatment. Common symptoms include wheezing, shortness of breath and chest pain, etc.
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Interstitial Lung Diseases
Respiratory MedicineCardio Thoracic Surgery
Interstitial lung disease leads to inflammation and scarring, making it difficult for the lungs to receive oxygen.
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Lung Cancer
Clinical OncologyGeneral SurgeryRespiratory MedicineCardio Thoracic Surgery
Lung cancer is a type of malignant tumor which is commonly caused by factors such as long-term smoking and air pollution, and requires early detection and treatment.
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Lung Nodule
Respiratory MedicineCardio Thoracic Surgery
Pulmonary nodules can be caused by non-cancerous conditions such as inflammation or benign growths, or they can be cancerous.
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Mediastinal Diseases
Respiratory MedicineCardio Thoracic Surgery
Mediastinal diseases possible causes of mediastinal diseases include lymph node enlargement (caused by infections, inflammation, autoimmune diseases, or malignancies), thymoma, abscess, malignant tumors, aortic aneurysm or esophageal disorders.
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Pleural Diseases (Pleural Effusion/ Pneumothorax)
Respiratory MedicineCardio Thoracic Surgery
Pleural effusion occurs when excess fluid accumulates in the space between the lung and chest wall, leading to symptoms like chest pain and shortness of breath.
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Pneumonia & Tuberculosis
Respiratory Medicine
Pneumonia is a lung infection that causes coughing, fever, and difficulty breathing. Tuberculosis (TB), on the other hand, is a lung infection that can spread through tiny droplets when an infected person coughs or sneezes. The initial symptoms of them are very similar.
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Respiratory Failure
Respiratory MedicineCardio Thoracic Surgery
Respiratory failure occurs when the lungs cannot adequately fulfill their essential function of supplying oxygen to the body and removing carbon dioxide. It can be caused by various factors such as lung diseases, infections, injuries, or even certain medications.
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Sleep apnea
OtolaryngologyRespiratory Medicine
Sleep apnea is a common form of sleep apnea, which is characterized by snoring and pauses in breathing. It requires treatment and lifestyle improvement.
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Therapeutic Bronchoscopy
Respiratory Medicine
Therapeutic bronchoscopy is a minimally invasive procedure that utilizes a flexible bronchoscope to diagnose and treat respiratory conditions.
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Upper Respiratory Tract Infection
Family MedicineRespiratory Medicine
Upper Respiratory Tract Infection (URTI) can be caused by bacterial or viral infection, commonly manifests as fever, sore throat and running nose, etc. It is usually self-limiting and recovered withing 3 weeks.
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